While Ausubel's work highlights the importance of a student's prior knowledge, it is Kirschner who makes the stronger point that "what we already know determines what, how, and how well we learn."
What do my students already know about the topic of my lesson?
How will I use what they know to help them relate to the new information?
If my students don't already know a lot about the topic I am teaching, what knowledge will I need to pre-teach to make the focus of my lesson more relatable, understandable and memorable?
Here is Kirschner's blog on the question of how prior knowledge determines what you can learn.